Journal: PLoS ONE
Article Title: A MicroRNA Signature Predicts Survival in Early Stage Small-Cell Lung Cancer Treated with Surgery and Adjuvant Chemotherapy
doi: 10.1371/journal.pone.0091388
Figure Lengend Snippet: (C) Correlation between expression of U6 RNA by qRT-PCR and log 2-transformed global mean array expression. (D) Expression of U6 RNA in human normal lung (NL, n = 3) and small-cell lung cancer (SCLC, n = 42) samples by microarray method. Whiskers depict the 10 and 90 percentiles. p value is calculated by the Mann-Whitney U test.
Article Snippet: Hybridization was performed using a custom microRNA microarray panel (CapitalBio, Beijing, China), which included probes in triplicate for 924 mature human and mouse miRNA sequences and eight short oligonucleotides that possessed no homology to any known RNA sequence as external controls.
Techniques: Expressing, Quantitative RT-PCR, Transformation Assay, Microarray, MANN-WHITNEY